본문 바로가기

Therapeutic response assessment using 3D ultrasound for hepatic metastasis from colorectal cancer: Application of a personalized, 3D-printed tumor model using CT images.

페이지 정보

작성자 profile_image최고관리자 작성일 19-04-15 17:29
31회 0건

본문

Abstract


BACKGROUND & AIMS:

To evaluate accuracy and reliability of three-dimensional ultrasound (3D US) for response evaluation of hepatic metastasis from colorectal cancer (CRC) using a personalized 3D-printed tumor model.


METHODS:

Twenty patients with liver metastasis from CRC who underwent baseline and after chemotherapy CT, were retrospectively included. Personalized 3D-printed tumor models using CT were fabricated. Two radiologists measured volume of each 3D printing model using 3D US. With CT as a reference, we compared difference between CT and US tumor volume. The response evaluation was based on Response Evaluation Criteria in Solid Tumors (RECIST) criteria.


RESULTS:

3D US tumor volume showed no significant difference from CT volume (7.18 ± 5.44 mL, 8.31 ± 6.32 mL vs 7.42 ± 5.76 mL in CT, p>0.05). 3D US provided a high correlation coefficient with CT (r = 0.953, r = 0.97) as well as a high inter-observer intraclass correlation (0.978; 0.958-0.988). Regarding response, 3D US was in agreement with CT in 17 and 18 out of 20 patients for observer 1 and 2 with excellent agreement (κ = 0.961).


CONCLUSIONS:

3D US tumor volume using a personalized 3D-printed model is an accurate and reliable method for the response evaluation in comparison with CT tumor volume.



  • 상호명 ㅣ 메디컬아이피
    대표이사 ㅣ 박상준    대표번호 ㅣ 02-2135-9148    사업자등록번호 ㅣ 406-81-04085
    사업장소재지 ㅣ 강원도 춘천시 강원대학길 1, 1204호 보듬관(효자동, 강원대학교)
Copyright2018. MEDICAL IP. All Rights Reserved.